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Home: Drug Pipeline   Print This Page 


Cancer Consultants Cancer Drug Pipeline



Leukemia
Drug Name Class Developer Phase
Abraxane
Nanoparticle formulation of taxane American Pharmaceuticals II  
AG-858 Vaccine Antigenics II (CML)
AMN107 Bcr-Abl, Kit, PDGFR inhibitor Novartis II
AP1903 Gene therapy Ariad Pharmaceuticals II
Arranon (nelarabine) Nucleoside analog GlaxoSmithKline Approved 10-28-05 T-ALL, T-LBL
BCX-1777 ONO inhibitor Biocryst I ALL
BL22 immunotoxin immunotoxin NCI II(Cladaribine resistant HCL
Campath (alemtuzumab) Monoclonal antibody Ilex Berlex III
Ceflatonin (homoharringtonine or HHT) Plant ankaloid Chem Genex I CML, APL
CEP-701 FLT3 inhibitor Cephalon II
Ceplene (histamine dihydrochloride) Synthetic nucleoside analog Maxim Pharmaceuticals III (AML)
Cloretazine (VNP4010M) Alkylating agent Vion II AML
Clofarex (clofarabine) Purine nucleoside Bioenvision II
Cloretazine (VNP4010M) DNA damaging alkylating agent VION I
CP461 Apoptotic antineoplastic Cell Pathways II
Dacogen (decitabine) DNA methyltransferase inhibitor MGI FDA submission(MDS)pending approval II AML, CML
Genasense (oblimersen) Antisense Genta and Aventis II (CML)
GTI-2040 Antisense Lorus Therapeutics II AML
GVAX Vaccine Cell Genesys II
GVH313 MoAb Gentic Therapy I CML
IDM-4 MoAb IDM Biotech I/II
Interleukin-2 Cytokine Valentis III (AML)
ISF154 Vaccine Tragen Pharmaceuticals II (CLL)
MG98 2nd generation antisense Methyl Gene I AML
MLN 518 Tyrosine kinase inhibitor (FLT3, PDGFR, c-KIT) Millennium II
Mylotarg (gemtuzumab) Monoclonal antibody Wyeth Approved and phase II (AML)
Onco TCS Liposomal vinca alkaloid Inex Enzon I ALL
Ontak (denileukin) Fusion protein Ligand Pharmaceuticals II
Peg-intron (peginterferon alfa-2b) Pegylated interferon alfa-2b Schering-Plough III
PKC412 (midostaurin) Tyrosine kinase inhibitor Novartis II
Remitogen (alpolizumab) MoAb Protein Desing Lab I/II ALL, CLL
Rituxan (rituximab) CD 20 monoclonal antibody Idec Pharmaceuticals and Genentech I,II
SAHA (superoylanilide hydroxamic acid HDAC inhibitor Aton I
Sarasar (lonafarnib) Oral Farnesyl Protein Transferase Inhibitor Schering-Plough II
SDX-101 (R-etodolac) Apoptotic Salmedix II
Siosix Recombinant human IL-6 Serono I AML
Taxotere (docetaxel) Taxoid Aventis II (ALL, AML)
Trisenox (arsenic trioxide) Arsenic Cell Therapeutics II (APL)
Troxatyl Troxacitibine deoxycytidine analogue Shire BioChem II
Zarnestra (tipifarnib) Farensyl transferase inhibitor Johnson & Johnson II
Zosuquidar trihydrochloride (LY335979) P-glycoprotein inhibitor Eli Lilly III (AML)
For more information contact us at clinicaltrials@cancerconsultants.com

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