Pathwork Diagnostics has launched the Pathwork tissue origin test, a microarray-based diagnostic test to help diagnose tumors of uncertain origin.
The Pathwork tissue test measures more than 1,500 genes, comparing the gene expression profile of the cancer with those of 15 known tissues, which represents more than 60 morphologies. The results provide a probability-based score for each potential tissue type.
An 89% sensitivity and 99% specificity score was achieved in a clinical validation study, including 487 poorly differentiated and undifferentiated metastatic tumors.
Reference: Pathwork Diagnostics. Now available through the CLIA-certified Pathwork Diagnostics Laboratory. Available at: http://www.pathworkdx.com/. Accessed May 2008.
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