The U.S. Food and Drug Administration (FDA) has granted SuperGen, Inc. orphan drug designation for their targeted agent MP-470 in the treatment of glioblastoma multiforme.
MP-470 is a tyrosine kinase inhibitor targeted against c-MET, c-RET, and the Rad51 protein, as well as mutant forms of c-KIT, PDGFR, and FLT3.
MP-470 is now being evaluated in Phase I trials as both a single agent and in combination with chemotherapy for the treatment of solid tumors. A Phase Ib trial is evaluating its efficacy in glioblastoma.
© 1998-2007 OncoEd.com All Rights Reserved.
These materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. All readers should verify all information and data before administering any drug, therapy or treatment discussed herein. Neither the editors nor the publisher accepts any responsibility for the accuracy of the information or consequences from the use or misuse of the information contained herein.
Patient Home
