Sentinel Node Biopsy for Thin Melanomas: Which Patient Should Be Considered?
Christopher A. Puleo, PA-C; Jane L. Messina, MD; Adam I. Riker, MD; L. Frank Glass, MD; Christopher Nelson, MD; C. Wayne Cruse, MD; Timothy M. Johnson, MD; Vernon K. Sondak, MD

Head and Neck Melanoma
Matthew A. Kienstra, MD; Tapan A. Padhya, MD

Choices in Adjuvant Therapy for Melanoma
David H. Lawson, MD

Cutaneous Melanoma: Prognostic Factors
Jade Homsi, MD, Mohammed Kashani-Sabet, MD, Jane L. Messina, MD, Adil Daud, MD

Chemoprevention of Melanoma: Theoretical and Practical Considerations
Marie-France Demierre, MD, FRCPC, Vernon K. Sondak, MD

Vaccines for Melanoma
C. Dean Buckner, MD

Adjuvant Radiotherapy Improves Local Control in High-risk Melanoma Patients (11/12/2009)
Researchers affiliated with the Intergroup Randomized Trial (TROG 01.01/ANZMTG 01.02) have reported that adjuvant radiotherapy (RT) improves regional control for patients with high-risk melanoma without a statistically significant effect on survival. The details of this study were presented at the 2009 meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO).

PLX4032, an Oncogenic BRAF-selective Inhibitor, Is Active in Advanced Melanoma (9/30/2009)
Researchers involved in a U.S.-Australian Phase I study have reported significant activity for PLX4032 in the treatment of patients with advanced melanoma. The details of this study were presented as a late-breaking abstract at the Joint ECCO 15-34^th ESMO Multidisciplinary Congress in Berlin, September 20-24, 2009.

Sutent® Has Antitumor Activity in Patients with Advanced Melanoma (9/24/2009)
Researchers from Belgium have reported that Sutent® (sunitinib) benefits one-third of patients with advanced malignant melanoma who have previously failed dacarbazine-based chemotherapy. The details of this Phase II study were presented at the Joint ECCO 15 – 34^th ESMO Multidisciplinary Congress in Berlin, September 20-24, 2009.

Full-body Skin Examination Detects Early Skin Melanomas (9/11/2009)
Researchers affiliated with North Florida Dermatology Associates have reported that more the half of all melanomas detected in their clinic were not found in patients presenting complaint and were earlier stage than those diagnosed following patients specific complaints. The details of this study appeared in the August 2009 issue of Archives of Dermatology.

Adjuvant Radiation Therapy May Improve Outcomes of Melanoma (9/4/2009)
Researchers from the M. D. Anderson Cancer Center have reported that adjuvant radiation therapy (RT) improves local control of melanoma following therapeutic lymph node dissection for lymph node-metastatic disease and may improve disease-specific survival. The details of this retrospective study were published early online in Cancer on August 21, 2009.